Symptoms of Creutzfeldt-Jakob Disease

Early Stages:

Memory failures
Behavioral changes
Difficulty in concentration and coordination
Visual disturbances
Myoclonus (a sudden rapid twitching resulting from the sudden contraction of one or more muscle groups)
Extensor plantar reflexes
Hyperflexia (exaggerated deep tendon reflexes)

Later (after the disease progresses):

Pronounced mental deterioration
Hemiparesis (muscular weakness or mild paralysis of one side of the body)
Sensory disturbances
Progressive muscular atrophy
Mutism (inability to speak)
Akinesia (loss or impairment of voluntary muscle action)
Seizures
Semicoma

Death usually occurs within a year, and may take place after only a few months.

Source: Jess G. Thoene, M.D. (Editor), Physicians' Guide to Rare Diseases, First Edition, 1992, Dowden Publishing Company)

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